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KMID : 0363319760010010085
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Journal of Korean Oriental Internal Medicine
1976 Volume.1 No. 1 p.85 ~ p.91
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EFFECT OF DIETARY GINSENG ON THE ACTIVITIES OF SERUM GLUTAMIC-PYRUVIC AND GLUTAMIC-OXALOACETIC TRANSAMINASES
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Abstract
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A chronicle intake of Substantial amount of alcohol would disrupt abnormal function of liver if not develop liver diseases in relatively short period.
In order to out whether ginseng or ginseng plus high protein diet have any protective effects on the liver of chronicle. alcoholist. from developing malfunction enzymatic activities of both glutamic-pyruvic and glutamic-oxaloacetic transamin-ases were measured oh serum of rats maintained with basal low protein diet, basal diet plus 1 percent ginseng and high protein (40%) plus 1 percent ginseng and administered intraperitoneally with a Constant amount of ethanol either periodically or chronically. It was found that, unlike human subject GOT content was exceedingly high and significant difference was found either among treatment or among sexes thus indicating that either ginseng intake or high protein diet plus ginseng has a protective effect on the liver function of ethanol treated rats.
From these results, it was suggested that the dietary ginseng might, have a protective effect on the alcohol hepatic disturbance. As one of probable mechanisms- for the characteristic pharmacological activity, it was considered that a secondary action of the saponin of the dietary ginseng would result in the anti-inflammatory through the stimulation of denove synthesis of certain functional proteins in hepatic organs.
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